Decide whether you need EHS, chemical compliance, or both, before you take a demo
Start here because it eliminates half the list in one step. Some of these platforms are built around chemical management and SDS/GHS authoring first (VelocityEHS, Sphera, EcoOnline); others are general incident/inspection/compliance suites that treat chemical data as one module among several (Benchmark Gensuite, Vector EHS Management, HSI Donesafe). If your plant handles hazardous materials and your last audit flagged SDS access or GHS labeling, start with the chemical-first vendors. If your gap is incident reporting, audits, and OSHA recordkeeping, the general EHS suites fit better and you won't pay for chemical-authoring depth you won't use.
Decide whether EHS needs to live next to quality or risk/claims
Three of the fifteen bundle EHS with an adjacent discipline in the same platform: Intelex and Ideagen EHS pair EHS with quality management, and Origami Risk pairs it with risk and claims management. If your quality team and safety team already fight over the same audit software, or your insurance broker wants claims data tied to incident records, that bundling saves an integration project. If they don't, it's a module you're paying to license and administer regardless.
Decide on company size fit before you request a demo
Four vendors here (Cority, Enablon, Sphera, Origami Risk) are listed as targeting enterprise accounts; eight (Intelex, EcoOnline, Evotix, Quentic, Ideagen EHS, KPA Flex, Vector EHS Management, HSI Donesafe) target mid-size. The remaining three (VelocityEHS, Benchmark Gensuite, Mitti) don't publish a stated target size. A 40-person plant asking an enterprise-targeted vendor for a quote will likely get a proposal built for a multi-site rollout, with the implementation cost that implies. Ask the vendor directly what a single-site, sub-100-employee deployment costs to implement, not just to license.
Decide who administers this day to day
EHS software fails when nobody owns it after the kickoff call ends. Ask each finalist who typically configures workflows post-launch: an EHS manager, an IT admin, or the vendor's professional services team on a retainer. Vector EHS Management and KPA Flex both mention advisory or training components alongside the software itself, which may signal built-in support, but confirm what's included versus billed separately.
Decide what it has to talk to
Safety software that can't get incident data into your existing quality system, or hazard data to the label printer on the floor, creates a second system of record nobody trusts. Ask specifically about integration with your ERP, your document control system, and (if chemical-first) your label printer and any downstream regulatory reporting tool. None of the fifteen listings here publish integration details, so this has to be a direct question to each vendor, not something you can shortlist on from this page alone.
Decide on pricing model last, because most won't tell you upfront
TODO(editor): verify the count of vendors offering a published price versus quote-only before publishing; confirm Mitti is the sole vendor with a listed per-seat rate.
Only one vendor on this list, Mitti (formerly SafetyCulture), publishes a rate: $24 per seat per month, with a free plan available. Every other vendor here is quote-only. That's normal for enterprise EHS software sold on annual contracts, but it means your Friday shortlist has to include a step where you request pricing from at least three vendors in parallel, because you cannot compare quotes you don't have yet.
TODO(editor): verify which of these fifteen vendors, if any, still ship an on-prem or hybrid deployment option; the listings block here shows cloud for all fifteen but that should be confirmed against each vendor's current site.
TODO(editor): verify whether the deployment listed for each vendor reflects their current offering, since directory entries can lag behind a vendor's own roadmap changes.